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  • 1.

    Petrova TV, Koh GY. Organic features of lymphatic vessels. Science. 2020;369(6500):eaax4063.

    CAS 
    PubMed 

    Google Scholar
     

  • 2.

    Mortimer PS, Rockson SG. New developments in scientific facets of lymphatic illness. The J Clin Make investments. 2014;124(3):915–21.

    CAS 
    PubMed 

    Google Scholar
     

  • 3.

    Zhang Y, Li Y, Tang S, Li X, Guan W, Li X, et al. Modified polymer dots for multi-scale multi-modal imaging of lymphatic system in tumor pre-metastasis. Appl Mater At the moment. 2020;21:100863.


    Google Scholar
     

  • 4.

    Clement CC, Rotzschke O, Santambrogio L. The lymph as a pool of self-antigens. Developments Immunol. 2011;32(1):6–11.

    CAS 
    PubMed 

    Google Scholar
     

  • 5.

    Alitalo Okay. The lymphatic vasculature in illness. Nat Med. 2011;17:1371–80.

    CAS 
    PubMed 

    Google Scholar
     

  • 6.

    Martin-Almedina S, Mortimer P, Ostergaard P. Improvement and physiological features of the lymphatic system-insights from genetic research of lymphedema. Physiol Rev. 2021;101:1809–71.

    PubMed 

    Google Scholar
     

  • 7.

    Randolph GJ, Ivanov S, Zinselmeyer BH, Scallan JP. The lymphatic system: integral roles in immunity. Annu Rev Immunol. 2017;35(1):31–52.

    CAS 
    PubMed 

    Google Scholar
     

  • 8.

    Kastenmüller W, Torabi-Parizi P, Subramanian N, Lämmermann T, Germain RN. A spatially-organized multicellular innate immune response in lymph nodes limits systemic pathogen unfold. Cell. 2012;150(6):1235–48.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 9.

    Tian R, Ke C, Rao L, Lau J, Chen X. Multimodal stratified imaging of nanovaccines in lymph nodes for enhancing most cancers immunotherapy. Adv Drug Deliv Rev. 2020;161–162:145–60.

    PubMed 

    Google Scholar
     

  • 10.

    Proulx ST, Luciani P, Dieterich LC, Karaman S, Leroux J-C, Detmar M. Growth of the lymphatic vasculature in most cancers and irritation: New alternatives for in vivo imaging and drug supply. J Managed Launch. 2013;172(2):550–7.

    CAS 

    Google Scholar
     

  • 11.

    Zhang F, Niu G, Lu G, Chen X. Preclinical lymphatic imaging. Mol Imaging Biol. 2011;13(4):599–612.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 12.

    Vl A, Lf B, Ii A. Biomedical nanotechnology: Occupational views-ScienceDirect. Nano At the moment. 2019;24:10–4.


    Google Scholar
     

  • 13.

    Jiang Y, Pu Okay. Superior photoacoustic imaging functions of near-infrared absorbing natural nanoparticles. Small. 2017;13(30):1700710.


    Google Scholar
     

  • 14.

    Kim YH, Im GB, Kim SW, Kim YJ, Yu T, Lee JR, et al. Anti-senescence ion-delivering nanocarrier for recovering therapeutic properties of long-term-cultured human adipose-derived stem cells. J Nanobiotechnology. 2021;19(1):352.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 15.

    Parodi A, Buzaeva P, Nigovora D, et al. Nanomedicine for rising the oral bioavailability of most cancers remedies. J Nanobiotechnol. 2021;19:354.


    Google Scholar
     

  • 16.

    Wang C, Fan W, Zhang Z, Wen Y, Chen X. Superior nanotechnology main the best way to multimodal imaging-guided precision surgical remedy. Adv Mater. 2019;31:1904329.

    CAS 

    Google Scholar
     

  • 17.

    Yang S, Chen C, Qiu Y, Xu C, Yao J. Being attentive to tumor blood vessels: most cancers phototherapy assisted with nano supply methods. Biomaterials. 2021;268:120562.

    CAS 
    PubMed 

    Google Scholar
     

  • 18.

    Han S, Wang W, Wang S, Yang T, Wang L, et al. Tumor microenvironment transforming and tumor remedy primarily based on M2-like tumor related macrophage-targeting nano-complexes. Theranostics. 2021;11(6):2892–916.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 19.

    Zhang T, Zheng Q, Fu Y, Xie C, Fan G, Wang Y, et al. α-Fe2O3@Pt heterostructure particles to allow sonodynamic remedy with self-supplied O2 and imaging-guidance. J Nanobiotechnol. 2021;19:358.


    Google Scholar
     

  • 20.

    Xc A, Yong Z. Mixture of tumor fragments and nanotechnology as a therapeutic method: Treating a tumor with tumor. Nano At the moment. 2020;35:100993.


    Google Scholar
     

  • 21.

    Music C, Zhang Y, Li C, Chen G, Kang X, Wan Q. Enhanced nanodrug supply to stable tumors primarily based on a tumor vasculature-targeted technique. Adv Funct Mater. 2016;26:4192–200.

    CAS 

    Google Scholar
     

  • 22.

    Wu H, Chen Z, Qi S, Bai B, Ye J, Wu D, et al. Analysis of the steadiness of cucurbit[8]uril-based ternary host-guest complexation in physiological atmosphere and the fabrication of a supramolecular theranostic nanomedicine. J Nanobiotechnology. 2021;19(1):330.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 23.

    Zhang Y, Li M, Gao X, Chen Y, Liu T. Nanotechnology in most cancers analysis: progress, challenges and alternatives. J Hematol Oncol. 2019;12:137.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 24.

    Li M, Gao X, Lin C, Shen A, Luo J, Ji Q, et al. An clever responsive macrophage cell membrane-camouflaged mesoporous silicon nanorod drug supply system for exact focused remedy of tumors. J Nanobiotechnology. 2021;19(1):336.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 25.

    Pieper CC, Hur S, Sommer CM, Nadolski G, Itkin M. Again to the long run: lipiodol in lymphography-from diagnostics to theranostics. Make investments Radiol. 2019;54(9):600–15.

    CAS 
    PubMed 

    Google Scholar
     

  • 26.

    Mellor RH, Hubert CE, Stanton A, Tate N, Mortimer PS. Lymphatic dysfunction, not aplasia, underlies Milroy illness. Microcirculation. 2010;17(4):281–96.

    CAS 
    PubMed 

    Google Scholar
     

  • 27.

    Mitsumori LM, McDonald ES, Wilson GJ, Neligan PC, Minoshima S, Maki JH. MR lymphangiography: How i do it. J Magn Reson Imaging. 2015;42:1465–77.

    PubMed 

    Google Scholar
     

  • 28.

    Yamamoto T, Yamamoto N, Numahata T, Yokoyama A, Tashiro Okay, Yoshimatsu H, et al. Navigation lymphatic supermicrosurgery for the remedy of cancer-related peripheral lymphedema. Vasc Endovascular Surg. 2014;48(2):139–43.

    PubMed 

    Google Scholar
     

  • 29.

    Kwon IG, Son T, Kim H, Hyung WJ. Fluorescent lymphography-guided lymphadenectomy throughout robotic radical gastrectomy for gastric most cancers. JAMA Surg. 2019;154(2):150–8.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 30.

    Natosha M, Trevor D, Mamadou LS, Nima Okay, Minhaj SK, Invoice SM. Lymphatic imaging methods. J Radiol Nurs. 2020;39(1):69–70.


    Google Scholar
     

  • 31.

    Dreyer Okay, van Rijswijk J, Mijatovic V, Goddijn M, Verhoeve HR, van Rooij IAJ, et al. Oil-based or water-based distinction for hysterosalpingography in infertile ladies. N Engl J Med. 2017;376(21):2043–52.

    CAS 
    PubMed 

    Google Scholar
     

  • 32.

    Kimura T, Hasegawa Okay, Morisada S, Inagawa Okay, Tsukahara Okay, Ensako T, et al. Lymphangiography and subsequent sclerotherapy may be simply utilized by cannulation of the lymph duct with a catheter for the neonatal central vein. Clin Case Rep. 2017;5(4):508–12.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 33.

    Ito H, Usui A, Uchida W, Mutsuga M. Usefulness of lymphography and computed tomography for detecting the positioning of chyle leakage. Indian J Thorac Cardiovasc Surg. 2019;35(1):104–7.

    PubMed 

    Google Scholar
     

  • 34.

    Hoogendam JP, Veldhuis WB, Hobbelink MG, Verheijen RH, van den Bosch MA, Zweemer RP. 99mTc SPECT/CT versus planar lymphoscintigraphy for preoperative sentinel lymph node detection in cervical most cancers: a scientific evaluate and metaanalysis. J Nucl Med. 2015;56(5):675–80.

    PubMed 

    Google Scholar
     

  • 35.

    Yoshida RY, Kariya S, Ha-Kawa S. Lymphoscintigraphy for imaging of the lymphatic circulate problems. Tech Vasc Interv Radiol. 2016;19(4):273–6.

    PubMed 

    Google Scholar
     

  • 36.

    Olmos R, Rietbergen D, Vidal-Sicart S. SPECT/CT and sentinel node lymphoscintigraphy. Clin Transl Imaging. 2014;2(6):491–504.


    Google Scholar
     

  • 37.

    Lerman H, Metser U, Lievshitz G, Sperber F, Shneebaum S, Even-Sapir E. Lymphoscintigraphic sentinel node identification in sufferers with breast most cancers: the function of SPECT-CT. Eur J Nucl Med Mol Imaging. 2006;33(3):329–37.

    CAS 
    PubMed 

    Google Scholar
     

  • 38.

    Pappalardo M, Cheng MH. Lymphoscintigraphy for the analysis of extremity lymphedema: present controversies relating to protocol, interpretation, and scientific utility. J Surg Oncol. 2020;121:37–47.

    PubMed 

    Google Scholar
     

  • 39.

    Kim EY, Hwang HS, Lee HY, Cho JH, Kim HK, Lee KS, et al. Anatomic and purposeful analysis of central lymphatics with noninvasive magnetic resonance lymphangiography. Drugs. 2016;95(12):e3109.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 40.

    Trinh L, Peterson P, Brorson H, Månsson S. Evaluation of subfascial muscle/water and fats accumulation in lymphedema sufferers utilizing magnetic resonance imaging. Lymphat Res Biol. 2019;17(3):340–6.

    PubMed 

    Google Scholar
     

  • 41.

    Mitsumori LM, Mcdonald ES, Neligan PC, Maki JH. Peripheral magnetic resonance lymphangiography: methods and functions. J Vasc Interv Radiol. 2016;19(4):262.


    Google Scholar
     

  • 42.

    Lohrmann C, Foeldi E, Bartholomae JP, Langer M. Gadoteridol for MR imaging of lymphatic vessels in lymphoedematous sufferers: Preliminary expertise after intracutaneous injection. Br J Radiol. 2007;80(955):569–73.

    CAS 
    PubMed 

    Google Scholar
     

  • 43.

    Krishnamurthy R, Hernandez A, Kavuk S, Annam A, Pimpalwar S. Imaging the central conducting lymphatics: preliminary expertise with dynamic MR lymphangiography. Radiology. 2015;274(3):871–8.

    PubMed 

    Google Scholar
     

  • 44.

    Ba Rrett T, Choyke PL, Kobayashi H. Imaging of the lymphatic system: new horizons. Distinction Media Mol Imaging. 2010;1(6):230–45.


    Google Scholar
     

  • 45.

    Landsman M, Kwant G, Mook GA, Zijlstra WG. Gentle-absorbing properties, stability, and spectal stabilization of indocyanine inexperienced. J Appl Physiol. 1976;40(4):575583.


    Google Scholar
     

  • 46.

    Polom Okay, Murawa D, Nowaczyk P, Rho YS, Murawa P. Breast most cancers sentinel lymph node mapping utilizing close to infrared guided indocyanine inexperienced and indocyanine green-human serum albumin as compared with gamma emitting radioactive colloid tracer. Eur J Surg Oncol. 2012;38(2):137–42.

    CAS 
    PubMed 

    Google Scholar
     

  • 47.

    Gashev AA, Nagai T, Bridenbaugh EA. Indocyanine inexperienced and lymphatic imaging: present issues. Lymphat Res Biol. 2010;8(2):127.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 48.

    Escobedo N, Oliver G. Lymphangiogenesis: origin, specification, and cell destiny dedication. Annu Rev Cell Dev Biol. 2016;32(1):677–91.

    CAS 
    PubMed 

    Google Scholar
     

  • 49.

    Dejana E, Orsenigo F. Endothelial adherens junctions at a look. J Cell Sci. 2013;126(12):2545–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 50.

    Dejana E, Orsenigo F, Molendini C, Baluk P, Mcdonald DM. Group and signaling of endothelial cell-to-cell junctions in varied areas of the blood and lymphatic vascular timber. Cell Tissue Res. 2009;335(1):17–25.

    PubMed 

    Google Scholar
     

  • 51.

    Dejana E, Tournier-Lasserve E, Weinstein BM. The management of vascular integrity by endothelial cell junctions: molecular foundation and pathological implications. Dev Cell. 2009;16(2):209–21.

    CAS 
    PubMed 

    Google Scholar
     

  • 52.

    Pfeiffer F, Kumar V, Butz S, Vestweber D, Imhof B, Stein J, et al. Distinct molecular composition of blood and lymphatic vascular endothelial cell junctions establishes particular purposeful obstacles throughout the peripheral lymph node. Eur J Immunol. 2010;38(8):2142–55.


    Google Scholar
     

  • 53.

    Sevick-Muraca EM, Kwon S, Rasmussen JC. Rising lymphatic imaging applied sciences for mouse and man. J Clin Make investments. 2014;124(3):905.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 54.

    Hsu MC, Itkin M. Lymphatic anatomy. Tech Vasc Interv Radiol. 2016;19(4):247–54.

    PubMed 

    Google Scholar
     

  • 55.

    Ryan GMK, Aminskas LM, Porter C. Nano-chemotherapeutics: Maximising lymphatic drug publicity to enhance the remedy of lymph-metastatic cancers. J Management Launch. 2014;193:241–56.

    CAS 
    PubMed 

    Google Scholar
     

  • 56.

    Irvine DJ, Swartz MA, Szeto GL, Irvine D, Swartz M, Szeto G. Engineering artificial vaccines utilizing cues from pure immunity. Nature Mater. 2013;12:978–90.

    CAS 

    Google Scholar
     

  • 57.

    Wiig H, Swartz MA. Interstitial fluid and lymph formation and transport: physiological regulation and roles in irritation and most cancers. Physiol Rev. 2012;92(3):1005–60.

    CAS 
    PubMed 

    Google Scholar
     

  • 58.

    Dixon JB. Lymphatic lipid transport: sewer or subway? Developments Endocrinol Metab. 2010;21(8):480–7.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 59.

    Thomas SN, Schudel A. Overcoming transport obstacles for interstitial-, lymphatic-, and lymph node-targeted drug supply. Curr Opin Chem Eng. 2015;7:65–74.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 60.

    Miteva D, Dixon B, Rutkowski J, Kilarski W, Shields J, Swartz M. Transmural circulate modulates cell and fluid transport features of lymphatic endothelium. Circ Res. 2010;106:920–31.

    CAS 
    PubMed 

    Google Scholar
     

  • 61.

    Jackson DG. Hyaluronan within the lymphatics: The important thing function of the hyaluronan receptor LYVE-1 in leucocyte trafficking. Matrix Biol. 2019;78–79:219–35.

    PubMed 

    Google Scholar
     

  • 62.

    Schubert W, Frank PG, Razani B, Park DS, Chow CW, Lisanti MP. Caveolae-deficient endothelial cells present defects within the uptake and transport of albumin in vivo. J Biol Chem. 2001;276(52):48619–22.

    CAS 
    PubMed 

    Google Scholar
     

  • 63.

    Xu W, Harris NR, Caron KM. Lymphatic vasculature: an rising therapeutic goal and drug supply route. Annu Rev Med. 2021;72(1):167–82.

    CAS 
    PubMed 

    Google Scholar
     

  • 64.

    Weiss M, Fan J, Claudel M, Sonntag T, Didier P, Ronzani C, et al. Density of floor cost is a extra predictive issue of the toxicity of cationic carbon nanoparticles than zeta potential. J Nanobiotechnol. 2021;19(1):5.

    CAS 

    Google Scholar
     

  • 65.

    Zeng Q, Jiang H, Wang T, Zhang Z, Gong T, Solar X. Cationic micelle supply of Trp2 peptide for environment friendly lymphatic draining and enhanced cytotoxic T lymphocyte responses. J Management Launch. 2015;200:1–12.

    CAS 
    PubMed 

    Google Scholar
     

  • 66.

    Lebre F, Hearnden CH, Lavelle EC. Modulation of immune responses by particulate supplies. Adv Mater. 2016;28:5525–41.

    CAS 
    PubMed 

    Google Scholar
     

  • 67.

    Rao DA, Forrest ML, Alani AW, Kwon GS, Robinson JR. Biodegradable PLGA primarily based nanoparticles for sustained regional lymphatic drug supply. J Pharm Sci. 2010;99(4):2018–31.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 68.

    Helle M, Rampazzo E, Monchanin M, Marchal F, Guillemin F, Bonacchi S, et al. Floor chemistry structure of silica nanoparticles decide the effectivity of in vivo fluorescence lymph node mapping. ACS Nano. 2013;7(10):8645–57.

    CAS 
    PubMed 

    Google Scholar
     

  • 69.

    Cordeiro AS, Crecente-Campo J, Bouzo BL, González SF, de la Fuente M, Alonso MJ. Engineering polymeric nanocapsules for an environment friendly drainage and biodistribution within the lymphatic system. J Drug Goal. 2019;27(5–6):646–58.

    CAS 
    PubMed 

    Google Scholar
     

  • 70.

    Park HS, Nam SH, Kim J, Shin HS, Suh YD, Hong KS. Clear-cut commentary of clearance of sustainable upconverting nanoparticles from lymphatic system of small residing mice. Sci Rep. 2016;6:27407.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 71.

    Ke X, Howard GP, Tang H, Cheng B, Saung MT, Santos JL, Mao HQ. Bodily and chemical profiles of nanoparticles for lymphatic concentrating on. Adv Drug Deliv Rev. 2019;151–152:72–93.

    PubMed 

    Google Scholar
     

  • 72.

    Yue ZG, Wei W, Lv PP, Yue H, Wang LY, Su ZG, Ma GH. Floor cost impacts mobile uptake and intracellular trafficking of chitosan-based nanoparticles. Biomacromol. 2011;12(7):2440–6.

    CAS 

    Google Scholar
     

  • 73.

    Tseng YC, Xu Z, Guley Okay, Yuan H, Huang L. Lipid-calcium phosphate nanoparticles for supply to the lymphatic system and SPECT/CT imaging of lymph node metastases. Biomaterials. 2014;35(16):4688–98.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 74.

    Kagan L, Gershkovich P, Mendelman A, Amsili S, Ezov N, Hoffman A. The function of the lymphatic system in subcutaneous absorption of macromolecules within the rat mannequin. Eur J Pharm Biopharm. 2007;67(3):759–65.

    CAS 
    PubMed 

    Google Scholar
     

  • 75.

    Oussoren C, Storm G. Liposomes to focus on the lymphatics by subcutaneous administration. Adv Drug Deliv Rev. 2001;50(1–2):143–56.

    CAS 
    PubMed 

    Google Scholar
     

  • 76.

    Chepurna OM, Yakovliev A, Ziniuk R, Nikolaeva OA, Levchenko SM, Xu H, et al. Core–shell polymeric nanoparticles co-loaded with photosensitizer and natural dye for photodynamic remedy guided by fluorescence imaging in close to and short-wave infrared spectral areas. J Nanobiotechnol. 2020;18:19.

    CAS 

    Google Scholar
     

  • 77.

    Zou X, Xu M, Yuan W, Wang Q, Shi Y, Feng W, et al. A water-dispersible dye-sensitized upconversion nanocomposite modified with phosphatidylcholine for lymphatic imaging. Chem Commun. 2016;52:13389–92.

    CAS 

    Google Scholar
     

  • 78.

    Niu G, Chen X. Lymphatic imaging: concentrate on imaging probes. Theranostics. 2015;5(7):686–97.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 79.

    Xu P, Hu L, Yu C, Yang W, Kang F, Zhang M, et al. Unsymmetrical cyanine dye by way of in vivo hitchhiking endogenous albumin affords high-performance NIR-II/photoacoustic imaging and photothermal remedy. J Nanobiotechnol. 2021;19(1):334.


    Google Scholar
     

  • 80.

    Akp A, Stp B. Imaging know-how of the lymphatic system. Adv Drug Deliv Rev. 2020;170:294–311.


    Google Scholar
     

  • 81.

    Donnell TF, Rasmussen JC, Sevick-Muraca EM. New diagnostic modalities within the analysis of lymphedema. J Vasc Surg Venous Lymphat Disord. 2017;5(2):261–73.


    Google Scholar
     

  • 82.

    Nieweg OE, Tanis PJ, Kroon B. The definition of a sentinel node. Ann Surg Oncol. 2001;8(6):538–41.

    CAS 
    PubMed 

    Google Scholar
     

  • 83.

    Vera DR, Wallace AM, Hoh CK, Mattrey RF. An artificial macromolecule for sentinel node detection: 99mTc-DTPA-mannosyl-dextran. J Nucl Med. 2001;42(6):951–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 84.

    Leong S, Kim J, Ross M, Faries M, Scoggins CR, Metz W, et al. A section 2 research of 99mTc-tilmanocept within the detection of sentinel lymph nodes in melanoma and breast most cancers. Ann Surg Oncol. 2011;18(4):961–9.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 85.

    Vidal-Sicart S, Rioja ME, Prieto A, Goñi E, Gómez I, Albala MD, et al. Sentinel lymph node biopsy in breast most cancers with 99mTc-tilmanocept: a multicenter research on real-life use of a novel tracer. J Nucl Med. 2021;62(5):620–7.

    CAS 
    PubMed 

    Google Scholar
     

  • 86.

    Xu Z, Wang Y, Han J, Xu Q, Ren J, Xu J, Wang Y, Chai Z. Noninvasive multimodal imaging of osteosarcoma and lymph nodes utilizing a 99mTc-labeled biomineralization nanoprobe. Anal Chem. 2018;90(7):4529–34.

    CAS 
    PubMed 

    Google Scholar
     

  • 87.

    Thorek DLJ, Ulmert D, Diop NFM, Lupu ME, Doran MG, Huang R, et al. Non-invasive mapping of deep-tissue lymph nodes in reside animals utilizing a multimodal PET/MRI nanoparticle. Nat Commun. 2014;5(1):3097.

    PubMed 

    Google Scholar
     

  • 88.

    Wang Y, Lang L, Huang P, Wang Z, Jacobson O, Kiesewetter DO, et al. In vivo albumin labeling and lymphatic imaging. Proc Natl Acad Sci U S A. 2015;112(1):208–13.

    PubMed 

    Google Scholar
     

  • 89.

    Lee SB, Yoon G, Lee SW, Jeong SY, Ahn BC, Lim DK, et al. Mixed positron emission tomography and cerenkov luminescence imaging of sentinel lymph nodes utilizing PEGylated radionuclide-embedded gold nanoparticles. Small. 2016;12(35):4894–901.

    CAS 
    PubMed 

    Google Scholar
     

  • 90.

    Shi X, Gao Okay, Xiong S, Gao R. Multifunctional transferrin encapsulated GdF3 nanoparticles for sentinel lymph node and tumor imaging. Bioconjug Chem. 2020;31(11):2576–84.

    CAS 
    PubMed 

    Google Scholar
     

  • 91.

    Xu G, Qian Y, Zheng H, Qiao S, Yan D, Lu L, et al. Lengthy-distance tracing of the lymphatic system with a computed tomography/fluorescence dual-modality nanoprobe for surveying tumor lymphatic metastasis. Bioconjug Chem. 2019;30(4):1199–209.

    CAS 
    PubMed 

    Google Scholar
     

  • 92.

    Hayashi S, Miyazaki M. Thoracic duct: visualization at nonenhanced MR lymphography-initial expertise. Radiology. 1999;212(2):598–600.

    CAS 
    PubMed 

    Google Scholar
     

  • 93.

    Villaraza AJ, Bumb A, Brechbiel MW. Macromolecules, dendrimers, and nanomaterials in magnetic resonance imaging: the interaction between dimension, perform, and pharmacokinetics. Chem Rev. 2010;110(5):2921–59.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 94.

    Solar C, Lee J, Zhang M. Magnetic nanoparticles in MR imaging and drug supply. Adv Drug Deliv Rev. 2008;60(11):1252–65.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 95.

    Kobayashi H, Kawamoto S, Choyke PL, Sato N, Knopp MV, et al. Comparability of dendrimer-based macromolecular distinction brokers for dynamic micro-magnetic resonance lymphangiography. Magn Reson Med. 2003;50(4):758–66.

    CAS 
    PubMed 

    Google Scholar
     

  • 96.

    Kobayashi H, Brechbiel MW. Nano-sized MRI distinction brokers with dendrimer cores. Adv Drug Deliv Rev. 2005;57(15):2271–86.

    CAS 
    PubMed 

    Google Scholar
     

  • 97.

    Müller A, Fries P, Jelvani B, Lux F, Rübe CE, Kremp S, et al. Magnetic resonance lymphography at 9.4 T utilizing a gadolinium-based nanoparticle in rats: investigations in wholesome animals and in a hindlimb lymphedema mannequin. Make investments Radiol. 2017;52(12):725–33.

    PubMed 

    Google Scholar
     

  • 98.

    Yano Okay, Matsumoto T, Okamoto Y, Kurokawa N, Hotta A. Fabrication of Gd-DOTA-functionalized carboxylated nanodiamonds for selective MR imaging (MRI) of the lymphatic system. Nanotechnology. 2021;32:235102.

    CAS 

    Google Scholar
     

  • 99.

    Saokar A, Braschi M, Harisinghani M. Lymphotrophic nanoparticle enhanced MR imaging (LNMRI) for lymph node imaging. Abdom Imaging. 2006;31(6):660–7.

    CAS 
    PubMed 

    Google Scholar
     

  • 100.

    Fan Z, Huang X, Qian C, Zhu L, Hida N, Gang N, et al. Synergistic enhancement of iron oxide nanoparticle and gadolinium for dual-contrast MRI. Biochem Biophys Res Commun. 2012;425(4):886–91.


    Google Scholar
     

  • 101.

    Zhang F, Zhu L, Huang X, et al. Differentiation of reactive and tumor metastatic lymph nodes with diffusion-weighted and SPIO-enhanced MRI. Mol Imaging Biol. 2013;15:40–7.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 102.

    Turkbey B, Czarniecki M, Shih JH, Harmon SA, Choyke PL. Ferumoxytol-enhanced MR lymphography for detection of metastatic lymph nodes in genitourinary malignancies: a potential research. AJR Am J Roentgenol. 2020;214(1):105–13.

    PubMed 

    Google Scholar
     

  • 103.

    Nie Y, Rui Y, Miao C, Li Q, Gu H. A secure USPIO succesful for MR lymphography with Extremely-low efficient dosage. Nanomedicine. 2020;29:102233.

    CAS 
    PubMed 

    Google Scholar
     

  • 104.

    Wu L, Mendoza-Garcia A, Li Q, Solar S. Natural section syntheses of magnetic nanoparticles and their functions. Chem Rev. 2016;116:10473–512.

    CAS 
    PubMed 

    Google Scholar
     

  • 105.

    Music G, Kenney M, Chen YS, Zheng X, Deng Y, Chen Z, et al. Carbon-coated FeCo nanoparticles as delicate magnetic-particle-imaging tracers with photothermal and magnetothermal properties. Nat Biomed Eng. 2020;4(3):325–34.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 106.

    Ma P, Luo Q, Chen J, Gan Y, Du J, Ding S, et al. Intraperitoneal injection of magnetic Fe3O4-nanoparticle induces hepatic and renal tissue harm by way of oxidative stress in mice. Int J Nanomedicine. 2012;7:4809–18.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 107.

    Giuseppe MF, Francesco G, Susanna G, Nevada CS, Duccio G, Paolo G, et al. MR lymphangiography: a sensible information to carry out it and a short evaluate of the literature from a technical perspective. Biomed Res Int. 2017;2017:1–8.


    Google Scholar
     

  • 108.

    Zeltzer AA, Carola B, Merel Okay, Randy DB, Benoit H, Moustapha H, Johan DM. MR lymphography in sufferers with higher limb lymphedema: The GPS for feasibility and surgical planning for lympho-venous bypass. J Surg Oncol. 2018;118(3):407–15.

    PubMed 

    Google Scholar
     

  • 109.

    Pons G, Clavero JA, Alomar X, Rodríguez-Bauza E, Tom LK, Masia J. Preoperative planning of lymphatico-venous anastomosis: using magnetic resonance lymphangiography as a complement to indocyanine inexperienced lymphography. J Plast Reconstr Aesthet Surg. 2019;72(6):884–91.

    CAS 
    PubMed 

    Google Scholar
     

  • 110.

    Nguyen QT, Tsien RY. Fluorescence-guided surgical procedure with reside molecular navigation–a brand new innovative. Nat Rev Most cancers. 2013;13(9):653–62.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 111.

    Chi C, Du Y, Ye J, Kou D, Qiu J, Wang J, et al. Intraoperative imaging-guided most cancers surgical procedure: from present fluorescence molecular imaging strategies to future multi-modality imaging know-how. Theranostics. 2014;4(11):1072–84.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 112.

    Ashitate Y, Hyun H, Kim SH, Lee JH, Henary M, Frangioni JV, Choi HS. Simultaneous mapping of pan and sentinel lymph nodes for real-time image-guided surgical procedure. Theranostics. 2014;4(7):693–700.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 113.

    Wada H, Hyun H, Vargas C, Gravier J, Park G, Gioux S, et al. Pancreas-targeted NIR fluorophores for dual-channel image-guided belly surgical procedure. Theranostics. 2015;5(1):1–11.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 114.

    Zhang NN, Lu CY, Chen MJ, Xu XL, Shu GF, Du YZ, Ji JS. Latest advances in near-infrared II imaging know-how for organic detection. J Nanobiotechnol. 2021;19(1):132.


    Google Scholar
     

  • 115.

    Wang S, Fan Y, Li D, Solar C, Lei Z, Lu L, et al. Anti-quenching NIR-II molecular fluorophores for in vivo high-contrast imaging and pH sensing. Nat Commun. 2019;10(1):1058.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 116.

    Wu W, Yang Y, Yang Y, Yang Y, Zhang Okay, Guo L, et al. Molecular engineering of an natural NIR-II fluorophore with aggregation-induced emission traits for in vivo imaging. Small. 2019;15(20):e1805549.

    PubMed 

    Google Scholar
     

  • 117.

    Kim S, Fisher B, Eisler HJ, Bawendi M. Sort-II quantum dots: CdTe/CdSe(core/shell) and CdSe/ZnTe(core/shell) heterostructures. J Am Chem Soc. 2003;125(38):11466–7.

    CAS 
    PubMed 

    Google Scholar
     

  • 118.

    Kim S, Lim YT, Soltesz EG, De Grand AM, Lee J, Nakayama A, et al. Close to-infrared fluorescent sort II quantum dots for sentinel lymph node mapping. Nat Biotechnol. 2004;22(1):93–7.

    CAS 
    PubMed 

    Google Scholar
     

  • 119.

    Bar-David S, Larush L, Goder N, Aizic A, Zigmond E, Varol C, et al. Dimension and lipid modification decide liposomal Indocyanine inexperienced efficiency for tumor imaging in a mannequin of rectal most cancers. Sci Rep. 2019;9(1):8566.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 120.

    Kraft JC, Ho RJ. Interactions of indocyanine inexperienced and lipid in enhancing near-infrared fluorescence properties: the premise for near-infrared imaging in vivo. Biochemistry. 2014;53(8):1275–83.

    CAS 
    PubMed 

    Google Scholar
     

  • 121.

    Crawford T, Moshnikova A, Roles S, Weerakkody D, DuPont M, Carter LM, et al. pHLIP ICG for delineation of tumors and blood circulate throughout fluorescence-guided surgical procedure. Sci Rep. 2020;10(1):18356.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 122.

    Poß M, Tower RJ, Napp J, Appold LC, Lammers T, Alves F, et al. Multimodal [GdO]+ [ICG]− nanoparticles for optical, photoacoustic, and magnetic resonance imaging. Chem Mater. 2017;29(8):3547–54.


    Google Scholar
     

  • 123.

    Proulx ST, Luciani P, Derzsi S, Rinderknecht M, Mumprecht V, Leroux JC, Detmar M. Quantitative imaging of lymphatic perform with liposomal indocyanine inexperienced. Most cancers Res. 2010;70(18):7053–62.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 124.

    Proulx ST, Luciani P, Christiansen A, Karaman S, Blum KS, Rinderknecht M, et al. Use of a PEG-conjugated shiny near-infrared dye for purposeful imaging of rerouting of tumor lymphatic drainage after sentinel lymph node metastasis. Biomaterials. 2013;34(21):5128–37.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 125.

    Kelley MC, Hansen N, McMasters KM. Lymphatic mapping and sentinel lymphadenectomy for breast most cancers. Am J Surg. 2004;188(1):49–61.

    PubMed 

    Google Scholar
     

  • 126.

    Leijte JA, van der Ploeg IM, Valdés Olmos RA, Nieweg OE, Horenblas S. Visualization of tumor blockage and rerouting of lymphatic drainage in penile most cancers sufferers by use of SPECT/CT. J Nucl Med. 2009;50(3):364–7.

    PubMed 

    Google Scholar
     

  • 127.

    Nathanson SD, Mahan M. Sentinel lymph node stress in breast most cancers. Ann Surg Oncol. 2011;18(13):3791–6.

    PubMed 

    Google Scholar
     

  • 128.

    Li C, Wang Q. Challenges and alternatives for intravital near-infrared fluorescence imaging know-how within the second transparency window. ACS Nano. 2018;12(10):9654–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 129.

    Kenry A, Duan Y, Liu B. Latest advances of optical imaging within the second near-infrared window. Adv Mater. 2018;30(47):e1802394.

    CAS 
    PubMed 

    Google Scholar
     

  • 130.

    He S, Music J, Qu J, Cheng Z. Essential breakthrough of second near-infrared organic window fluorophores: design and synthesis towards multimodal imaging and theranostics. Chem Soc Rev. 2018;47(12):4258–78.

    CAS 
    PubMed 

    Google Scholar
     

  • 131.

    Ding F, Zhan Y, Lu X, Solar Y. Latest advances in near-infrared II fluorophores for multifunctional biomedical imaging. Chem Sci. 2018;9(19):4370–80.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 132.

    Cai Z, Zhu L, Wang M, Roe AW, Xi W, Qian J. NIR-II fluorescence microscopic imaging of cortical vasculature in non-human primates. Theranostics. 2020;10(9):4265–76.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 133.

    Carr JA, Franke D, Caram JR, Perkinson CF, Saif M, Askoxylakis V, et al. Shortwave infrared fluorescence imaging with the clinically permitted near-infrared dye indocyanine inexperienced. Proc Natl Acad Sci U S A. 2018;115(17):4465–70.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 134.

    Tian R, Ma H, Zhu S, Lau J, Ma R, Liu Y, et al. Multiplexed NIR-II probes for lymph node-invaded most cancers detection and imaging-guided surgical procedure. Adv Mater. 2020;32(11):e1907365.

    PubMed 

    Google Scholar
     

  • 135.

    Fang Y, Li Y, Li Y, He R, Zhang Y, Zhang X, et al. In situ protease secretion visualization and metastatic lymph nodes imaging by way of a cell membrane-anchored upconversion nanoprobe. Anal Chem. 2021;93(19):7258–65.

    CAS 
    PubMed 

    Google Scholar
     

  • 136.

    Wang Z, Xia H, Chen B, Wang Y, Yin Q, Yan Y, et al. pH-Amplified CRET nanoparticles for in vivo imaging of tumor metastatic lymph nodes. Angew Chem Int Ed Engl. 2021;60(26):14512–20.

    CAS 
    PubMed 

    Google Scholar
     

  • 137.

    Shi L, Wang Y, Zhang C, Zhao Y, Lu C, Yin B, et al. An acidity-unlocked magnetic nanoplatform permits self-boosting ROS era via upregulation of lactate for imaging-guided extremely particular chemodynamic remedy. Angew Chem Int Ed Engl. 2021;60(17):9562–72.

    CAS 
    PubMed 

    Google Scholar
     

  • 138.

    Ma Y, Xu L, Yin B, Shang J, Chen F, Xu J, et al. Ratiometric semiconducting polymer nanoparticle for dependable photoacoustic imaging of pneumonia-induced weak atherosclerotic plaque in vivo. Nano Lett. 2021;21(10):4484–93.

    CAS 
    PubMed 

    Google Scholar
     

  • 139.

    Teng L, Han X, Liu Y, Lu C, Yin B, Huan S, et al. Sensible nanozyme platform with activity-correlated ratiometric molecular imaging for predicting therapeutic results. Angew Chem Int Ed Engl. 2021;60(50):26142–50.

    CAS 
    PubMed 

    Google Scholar
     

  • 140.

    Fan F, Yu Y, Zhong F, Gao M, Solar T, Liu J, et al. Design of tumor acidity-responsive sheddable nanoparticles for fluorescence/magnetic resonance imaging-guided photodynamic remedy. Theranostics. 2017;7(5):1290–302.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 141.

    Fang Z, Pan S, Gao P, Sheng H, Li L, Shi L, et al. Stimuli-responsive charge-reversal nano drug supply system: The promising focused carriers for tumor remedy. Int J Pharm. 2020;575:118841.

    CAS 
    PubMed 

    Google Scholar
     

  • 142.

    Liu J, Wu Y, Fu C, Li B, Li L, Zhang R, et al. Cost reversion concurrently enhances tumor accumulation and cell uptake of layered double hydroxide nanohybrids for efficient imaging and remedy. Small. 2020;16(31):e2002115.

    PubMed 

    Google Scholar
     

  • 143.

    Wu J, Zheng Y, Liu M, Shan W, Zhang Z, Huang Y. Biomimetic viruslike and cost reversible nanoparticles to sequentially overcome mucus and epithelial obstacles for oral insulin supply. ACS Appl Mater Interfaces. 2018;10(12):9916–28.

    CAS 
    PubMed 

    Google Scholar
     

  • 144.

    Birks JB. Photophysics of fragrant molecules-a postscript. Org Mol Photophys. 1975;2:409–613.

    CAS 

    Google Scholar
     

  • 145.

    Luo J, Xie Z, Lam JW, Cheng L, Chen H, Qiu C, et al. Aggregation-induced emission of 1-methyl-1,2,3,4,5-pentaphenylsilole. Chem Commun. 2001;18:1740–1.


    Google Scholar
     

  • 146.

    Liang J, Feng G, Kwok RTK, Ding D, Tang BZ, Liu B. AIEgen primarily based light-up probes for reside cell imaging. Sci China Chem. 2016;59:53–61.

    CAS 

    Google Scholar
     

  • 147.

    Hu R, Qin A, Tan BZ. AIE polymers: Synthesis and functions. Prog Polym Sci. 2019;100:101176.


    Google Scholar
     

  • 148.

    Xie H, Li Z, Gong J, Hu L, Alam P, Ji X, et al. Phototriggered aggregation-induced emission and direct era of 4D mushy patterns. Adv Mater. 2021;23:e2105113.


    Google Scholar
     

  • 149.

    Fan X, Li Y, Feng Z, Chen G, Zhou J, He M, et al. Nanoprobes-assisted multichannel NIR-II fluorescence imaging-guided resection and photothermal ablation of lymph nodes. Adv Sci. 2021;8(9):2003972.

    CAS 

    Google Scholar
     

  • 150.

    Kim C, Favazza C, Wang LV. In vivo photoacoustic tomography of chemical compounds: high-resolution purposeful and molecular optical imaging at new depths. Chem Rev. 2010;110(5):2756–82.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 151.

    Wang S, Lin J, Wang T, Chen X, Huang P. Latest advances in photoacoustic imaging for deep-tissue biomedical functions. Theranostics. 2016;6(13):2394–413.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 152.

    Music KH, Stein EW, Margenthaler JA, Wang LV. Noninvasive photoacoustic identification of sentinel lymph nodes containing methylene blue in vivo in a rat mannequin. J Biomed Choose. 2008;13(5):054033.

    PubMed 

    Google Scholar
     

  • 153.

    Pan D, Pramanik M, Senpan A, Ghosh S, Wickline SA, Wang LV, Lanza GM. Close to infrared photoacoustic detection of sentinel lymph nodes with gold nanobeacons. Biomaterials. 2010;31(14):4088–93.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 154.

    Wu L, Cai X, Nelson Okay, Xing W, Xia J, Zhang R, et al. A inexperienced synthesis of carbon nanoparticle from honey for real-time photoacoustic imaging. Nano Res. 2013;6(5):312–25.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 155.

    Rieffel J, Chen F, Kim J, Chen G, Shao W, et al. Hexamodal imaging with porphyrin-phospholipid-coated upconversion nanoparticles. Adv Mater. 2015;27(10):1785–90.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 156.

    Liu X, Lee C, Regulation WC, Zhu D, Liu M, Jeon M, et al. Au-Cu(2–x)Se heterodimer nanoparticles with broad localized floor plasmon resonance as distinction brokers for deep tissue imaging. Nano Lett. 2013;13(9):4333–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 157.

    Luke GP, Bashyam A, Homan KA, Makhija S, Chen YS, Emelianov SY. Silica-coated gold nanoplates as secure photoacoustic distinction brokers for sentinel lymph node imaging. Nanotechnology. 2013;24(45):455101.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 158.

    Lee C, Kim J, Zhang Y, Jeon M, Liu C, Music L, Lovell JF, Kim C. Twin-color photoacoustic lymph node imaging utilizing nanoformulated naphthalocyanines. Biomaterials. 2015;73:142–8.

    CAS 
    PubMed 

    Google Scholar
     

  • 159.

    Liu Z, Chen X. Easy bioconjugate chemistry serves nice scientific advances: albumin as a flexible platform for analysis and precision remedy. Chem Soc Rev. 2016;45(5):1432–56.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 160.

    Du B, Qu C, Qian Okay, Ren Y, Cheng Z. An IR820 dye-protein complicated for second near-infrared window and photoacoustic imaging. Adv Choose Mater. 2019;34:1901471.


    Google Scholar
     

  • 161.

    Mallidi S, Watanabe Okay, Timerman D, Schoenfeld D, Hasan T. Prediction of tumor recurrence and remedy monitoring utilizing ultrasound-guided photoacoustic imaging. Theranostics. 2015;5(3):289–301.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 162.

    Khalili Fard J, Jafari S, Eghbal MA. A evaluate of molecular mechanisms concerned in toxicity of nanoparticles. Adv Pharm Bull. 2015;5(4):447–54.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 163.

    Laufer J, Jathoul A, Pule M, Beard P. In vitro characterization of genetically expressed absorbing proteins utilizing photoacoustic spectroscopy. Biomed Choose Categorical. 2013;4(11):2477–90.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 164.

    Roberts S, Strome A, Choi C, Andreou C, Kossatz S, Model C, et al. Acid particular darkish quencher QC1 pHLIP for multi-spectral optoacoustic diagnoses of breast most cancers. Sci Rep. 2019;9(1):8550.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 165.

    Cardinell Okay, Gupta N, Koivisto BD, Kumaradas JC, Zhou X, Irving H, et al. A novel photoacoustic-fluorescent distinction agent for quantitative imaging of lymphatic drainage. Photoacoustics. 2021;21:100239.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 166.

    Dewitte H, Vanderperren Okay, Haers H, Inventory E, Duchateau L, Hesta M, et al. Theranostic mRNA-loaded microbubbles within the lymphatics of canine: implications for drug supply. Theranostics. 2015;5(1):97–109.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 167.

    Liberman A, Martinez HP, Ta CN, Barback CV, Mattrey RF, Kono Y, et al. Hole silica and silica-boron nano/microparticles for contrast-enhanced ultrasound to detect small tumors. Biomaterials. 2012;33(20):5124–9.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 168.

    El Kaffas A, Sigrist RMS, Fisher G, Bachawal S, Liau J, Wang H, et al. Quantitative three-dimensional dynamic contrast-enhanced ultrasound imaging: first-in-human pilot research in sufferers with liver metastases. Theranostics. 2017;7(15):3745–58.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 169.

    Lurie DM, Seguin B, Schneider PD, Verstraete FJ, Wisner ER. Distinction-assisted ultrasound for sentinel lymph node detection in spontaneously arising canine head and neck tumors. Make investments Radiol. 2006;41(4):415–21.

    PubMed 

    Google Scholar
     

  • 170.

    Goldberg BB, Merton DA, Liu JB, Thakur M, Murphy GF, Needleman L, et al. Sentinel lymph nodes in a swine mannequin with melanoma: contrast-enhanced lymphatic US. Radiology. 2004;230(3):727–34.


    Google Scholar
     

  • 171.

    Horstmann J, Schulz-Hildebrandt H, Bock F, Siebelmann S, Lankenau E, Hüttmann G, et al. Label-free in vivo imaging of corneal lymphatic vessels utilizing microscopic optical coherence tomography. Make investments Ophthalmol Vis Sci. 2017;58(13):5880–6.

    CAS 
    PubMed 

    Google Scholar
     

  • 172.

    Keahey P, Si P, Razavi M, Yu S, Lippok N, Villiger M, et al. Spectral- and polarization-dependent scattering of gold nanobipyramids for exogenous distinction in optical coherence tomography. Nano Lett. 2021;21(20):8595–601.

    CAS 
    PubMed 

    Google Scholar
     

  • 173.

    Kobayashi H, Koyama Y, Barrett T, Hama Y, Regino CA, Shin IS, et al. Multimodal nanoprobes for radionuclide and five-color near-infrared optical lymphatic imaging. ACS Nano. 2007;1(4):258–64.

    CAS 
    PubMed 
    PubMed Central 

    Google Scholar
     

  • 174.

    Zhou J, Zhu X, Chen M, Solar Y, Li F. Water-stable NaLuF4-based upconversion nanophosphors with long-term validity for multimodal lymphatic imaging. Biomaterials. 2012;33(26):6201–10.

    CAS 
    PubMed 

    Google Scholar
     

  • 175.

    Ni D, Ehlerding EB, Cai W. Multimodality Imaging Brokers with PET because the Elementary Pillar. Angew Chem Int Ed Engl. 2019;58(9):2570–9.

    CAS 
    PubMed 

    Google Scholar
     

  • 176.

    Phillips E, Penate-Medina O, Zanzonico PB, Carvajal RD, Mohan P, Ye Y, et al. Medical translation of an ultrasmall inorganic optical-PET imaging nanoparticle probe. Sci Transl Med. 2014;6(260):260ra149.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 177.

    Lengthy X, Zhang J, Zhang D, Gao C, Chi C, Yang E, et al. Microsurgery guided by sequential preoperative lymphography utilizing 68Ga-NEB PET and MRI in sufferers with lower-limb lymphedema. Eur J Nucl Med Mol Imaging. 2017;44(9):1501–10.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 178.

    Zhu G, Lynn GM, Jacobson O, Chen Okay, Liu Y, Zhang H, et al. Albumin/vaccine nanocomplexes that assemble in vivo for mixture most cancers immunotherapy. Nat Commun. 2017;8(1):1954.

    PubMed 
    PubMed Central 

    Google Scholar
     

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