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Reactive oxygen species (ROS)-responsive nanoprobe for bioimaging and concentrating on remedy of osteoarthritis | Journal of Nanobiotechnology

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  • 1.

    Cross M, Smith E, Hoy D, Nolte S, Ackerman I, Fransen M, Bridgett L, Williams S, Guillemin F, Hill CL, Laslett LL, Jones G, Cicuttini F, Osborne R, Vos T, Buchbinder R, Woolf A, March L. The worldwide burden of hip and knee osteoarthritis: estimates from the worldwide burden. Ann Rheum Dis. 2014;73:1323–30.

    PubMed 

    Google Scholar
     

  • 2.

    Holt HL, Katz JN, Reichmann WM, Gerlovin H, Wright EA, Hunter DJ, Jordan JM, Kessler CL, Losina E. Forecasting the burden of superior knee osteoarthritis over a 10-year interval in a cohort of 60–64 year-old US adults. Osteoarthr Cartil. 2011;19:44–50.

    CAS 

    Google Scholar
     

  • 3.

    Bijlsma JWJ, Berenbaum F, Lafeber FPJG. Osteoarthritis: an replace with relevance for medical observe. Lancet. 2011;377:2115–26.

    PubMed 

    Google Scholar
     

  • 4.

    Jin P, Wiraja C, Zhao JM, Zhang JL, Zheng L, Chenjie Xu CJ. Nitric oxide nanosensors for predicting the event of osteoarthritis in rat. ACS Appl Mater Interfaces. 2017;9:25128–37.

    PubMed 
    CAS 

    Google Scholar
     

  • 5.

    Lee S, Park Okay, Lee SY, Ryu JH, Park JW, Ahn HJ, Kwon IC, Youn IC, Kim Okay, Choi Okay. Darkish quenched matrix metalloproteinase fluorogenic probe for imaging osteoarthritis. Bioconjug Chem. 2008;19:1743–7.

    PubMed 
    CAS 

    Google Scholar
     

  • 6.

    Castano AD, Lim NH, Tranchant I, Amoura M, Beau F, Wieland H, Kingler O, Herrmann M, Nazaré M, Plettenburg O, Dive V, Vicent MJ, Nagase H. In vivo imaging of MMP-13 exercise utilizing a particular polymer-FRET peptide conjugate detects early osteoarthritis and inhibitor efficacy. Adv Funct Mater. 2018;28:37.


    Google Scholar
     

  • 7.

    Lim NH, Meinjohanns E, Meldal M, Gharios GB, Nagase H. In vivo imaging of MMP-13 exercise within the murine destabilised medial meniscus. Osteoarthr Cartil. 2014;22:862–8.

    CAS 

    Google Scholar
     

  • 8.

    Ryu JH, Lee A, Lee S, Ahn CH, Park JW, Leary JF, Park S, Kim Okay, Kwon IC, Youn I-C, Choi Okay. “One-step” detection of matrix metalloproteinase exercise utilizing a fluorogenic peptide probe-immobilized diagnostic package. Bioconjug Chem. 2010;21:1378–84.

    PubMed 
    CAS 

    Google Scholar
     

  • 9.

    Bellucci F, Meini S, Cucchi P, Catalani C, Nizzardo A, Riva A, Guidelli GM, Ferrata P, Fioravanti A, Maggi CA. Synovial fluid ranges of bradykinin correlate with biochemical markers for cartilage. Osteoarthr Cartil. 2013;21:1774–80.

    CAS 

    Google Scholar
     

  • 10.

    Karan A, Karan MA, Vural P, Erten N, Taşçioğlu C, Aksoy C, Canbaz M, Oncel A. Synovial fluid nitric oxide ranges in sufferers with knee osteoarthritis. Clin Rheumatol. 2003;22(6):397–9.

    PubMed 

    Google Scholar
     

  • 11.

    Maher MC, Schnabel LV, Cross JA, Papich MG, Divers TJ, Fortier LA. Plasma and synovial fluid focus of doxycycline following low-dose, low-frequency administration, and resultant inhibition of matrix metalloproteinase-13 from interleukin-stimulated equine synoviocytes. Equine Vet J. 2014;46:198–202.

    PubMed 
    CAS 

    Google Scholar
     

  • 12.

    Beekman B, El BV, Drijfhout JW, Ronday HK, TeKoppele JM. Extremely elevated ranges of lively stromelysin in rheumatoid synovial fluid decided by a selective fluorogenic assay. FEBS Lett. 1997;418:305–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 13.

    Lepetsos P, Papavassiliou AG. ROS/oxidative stress signaling in osteoarthritis. Biochim Biophys Acta. 2016;1862:576–91.

    PubMed 
    CAS 

    Google Scholar
     

  • 14.

    Yao YJ, Zhang HL, Wang ZY, Ding J, Wang SQ, Huang BQ, Ke SF, Gao CY. Reactive oxygen species (ROS)-responsive biomaterials mediate tissue microenvironments and tissue regeneration. J Mater Chem B. 2019;7:5019–37.

    PubMed 
    CAS 

    Google Scholar
     

  • 15.

    Lotito APN, Muscará MN, Kiss MHB, Teixeira SA, Novaes GS, Laurindo IMM, Silva CA, Mello SBV. Nitric oxide-derived species in synovial fluid from sufferers with juvenile idiopathic arthritis. J Rheumatol. 2004;31:992–7.

    PubMed 
    CAS 

    Google Scholar
     

  • 16.

    Hosseinzadeh A, Kamrava SK, Joghataei MT, Darabi R, Zadeh AS, Shahriari M, Reiter RJ, Ghaznavi H, Mehrzadi S. Apoptosis signaling pathways in osteoarthritis and doable protecting function of melatonin. J Pineal Res. 2016;61:411–25.

    PubMed 
    CAS 

    Google Scholar
     

  • 17.

    Yuan YY, Liu J, Liu B. Conjugated-polyelectrolyte-based polyprodrug: focused and image-guided photodynamic and chemotherapy with on-demand drug launch upon irradiation with a single gentle supply. Angew Chem Int Ed Engl. 2014;53:7163–8.

    PubMed 
    CAS 

    Google Scholar
     

  • 18.

    Lee S, Stubelius A, Hamelmann N, Tran V, Almutairi A. Irritation-responsive drug-conjugated dextran nanoparticles improve anti-inflammatory drug efficacy. ACS Appl Mater Interfaces. 2018;10:40378–87.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 19.

    Kim EJ, Bhuniya S, Lee H, Kim HM, Cheong C, Maiti S, Hong KS, Kim JS. An activatable prodrug for the remedy of metastatic tumors. J Am Chem Soc. 2014;136:13888–94.

    PubMed 
    CAS 

    Google Scholar
     

  • 20.

    Lv W, Xu JP, Wang XQ, Li XR, Xu QW, Xin HL. Bioengineered boronic ester modified dextran polymer nanoparticles as reactive oxygen species responsive nanocarrier for ischemic stroke remedy. ACS Nano. 2018;12:5417–26.

    PubMed 
    CAS 

    Google Scholar
     

  • 21.

    Yang B, Wang KY, Zhang D, Solar BJ, Ji B, Wei L, Li ZB, Wang ML, Zhang XB, Zhang HT, Kan QM, Luo C, Wang YJ, He ZG, Solar J. Mild-activatable dual-source ROS-responsive prodrug nanoplatform for synergistic chemo-photodynamic remedy. Biomater Sci. 2018;6:2965–75.

    PubMed 
    CAS 

    Google Scholar
     

  • 22.

    Jung E, Noh JY, Kang CS, Yoo D, Music C, Lee D. Ultrasound imaging and on-demand remedy of peripheral arterial ailments utilizing H2O2-activated bubble producing anti-inflammatory polymer particles. Biomaterials. 2018;179:175–85.

    PubMed 
    CAS 

    Google Scholar
     

  • 23.

    Kang CS, Cho W, Park M, Kim J, Park S, Shin D, Music C, Lee D. H2O2-triggered bubble producing antioxidant polymeric nanoparticles as ischemia/reperfusion focused nanotheranostics. Biomaterials. 2016;85:195–203.

    PubMed 
    CAS 

    Google Scholar
     

  • 24.

    Kim S, Park H, Music Y, Hong D, Kim O, Jo E, Khang G, Lee D. Discount of oxidative stress by p-hydroxybenzyl alcohol-containing biodegradable polyoxalate nanoparticulate antioxidant. Biomaterials. 2011;32:3021–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 25.

    Xu XD, Noticed PE, Tao W, Li YJ, Ji XY, Bhasin S, Liu YL, Ayyash D, Rasmussen J, Huo M, Shi JJ, Farokhzad OC. ROS-responsive polyprodrug nanoparticles for triggered drug supply and efficient most cancers remedy. Adv Mater. 2017;29:201700141.


    Google Scholar
     

  • 26.

    Zhang WJ, Hu XL, Shen Q, Xing D. Mitochondria-specific drug launch and reactive oxygen species burst induced by polyprodrug nanoreactors can improve chemotherapy. Nat Commun. 2019;10:1704.

    PubMed 
    PubMed Central 

    Google Scholar
     

  • 27.

    Cheng DB, Zhang XH, Yu-Juan Gao YJ, Ji L, Hou DY, Wang ZQ, Xu WH, Qiao ZY, Wang H. Endogenous reactive oxygen species-triggered morphology transformation for enhanced cooperative interplay with mitochondria. J Am Chem Soc. 2019;141:7235–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 28.

    Kavanaugh TE, Werfel TA, Cho H, Hasty KA, Duvall CL. Particle-based applied sciences for osteoarthritis detection and remedy. Drug Deliv Transl Res. 2016;6:132–47.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 29.

    Rothenfluh DA, Bermudez H, O’Neil CP, Hubbell JA. Biofunctional polymer nanoparticles for intra-articular concentrating on and retention in cartilage. Nat Mater. 2008;7:248–54.

    PubMed 
    CAS 

    Google Scholar
     

  • 30.

    Maeda H, Nakamura H, Fang J. The EPR impact for macromolecular drug supply to stable tumors: enchancment of tumor uptake, reducing of systemic toxicity, and distinct tumor imaging in vivo. Adv Drug Deliv Rev. 2013;65:71–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 31.

    Ouyang ZX, Tan TT, Liu CF, Duan J, Wang WC, Guo XN, Zhang Q, Li ZL, Huang QL, Dou PC, Liu T. Focused supply of hesperetin to cartilage attenuates osteoarthritis by bimodal imaging with Gd 2(CO3)3@PDA nanoparticles through TLR-2/NF-κB/Akt signaling. Biomaterials. 2019;205:50–63.

    PubMed 
    CAS 

    Google Scholar
     

  • 32.

    Pi YB, Zhang X, Shi JJ, Zhu JX, Chen WQ, Zhang CG, Gao WW, Zhou CY, Ao YF. Focused supply of non-viral vectors to cartilage in vivo utilizing a chondrocyte-homing peptide recognized by phage show. Biomaterials. 2011;32:6324–32.

    PubMed 
    CAS 

    Google Scholar
     

  • 33.

    Lu YHCS, Evans CH, Grodzinsky AJ. Results of short-term glucocorticoid remedy on modifications in cartilage matrix degradation and chondrocyte gene expression induced by mechanical damage and inflammatory cytokines. Arthritis Res Ther. 2011;13:R142.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 34.

    Asadullah Okay, Schäcke H, Cato ACB. Dichotomy of glucocorticoid motion within the immune system. Developments Immunol. 2002;23:120–2.

    PubMed 
    CAS 

    Google Scholar
     

  • 35.

    Huebner KD, Shrive NG, Frank CB. Dexamethasone inhibits irritation and cartilage harm in a brand new mannequin of post-traumatic osteoarthritis. J Orthop Res. 2014;32:566–72.

    PubMed 
    CAS 

    Google Scholar
     

  • 36.

    Rao ZT, Wang SQ, Wang JQ. Peroxiredoxin 4 inhibits IL-1β-induced chondrocyte apoptosis through PI3K/AKT signaling. Biomed Pharmacother. 2017;90:414–20.

    PubMed 
    CAS 

    Google Scholar
     

  • 37.

    Santos MV, Rocha LB, Vieira EG, Oliveira AL, Lobo AO, Carvalho MA, Osajima JA, Silva-Filho EC. Growth of composite scaffolds primarily based on cerium doped-hydroxyapatite and pure gums-biological and mechanical properties. Supplies. 2019;12:2389.


    Google Scholar
     

  • 38.

    Jiang LP, Li LJ, Geng CY, Gong DZ, Jiang LJ, Ishikawa N, Kajima Okay, Zhong LF. Monosodium iodoacetate induces apoptosis through the mitochondrial pathway involving ROS manufacturing and caspase activation in rat chondrocytes in vitro. J Orthop Res. 2013;31:364–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 39.

    Morita Okay, Miyamoto T, Fujita N, Kubota Y, Ito Okay, Takubo Okay, Miyamoto Okay, Ninomiya Okay, Suzuki T, Iwasaki R, Yagi M, Takaishi H, Toyama Y, Suda T. Reactive oxygen species induce chondrocyte hypertrophy in endochondral ossification. J Exp Med. 2007;204:1613–23.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 40.

    Park C, Jeong JW, Lee DS, Yim MJ, Lee JM, Han MH, Kim S, Kim HS, Kim GY, Park EK, You- Jeon J, Cha HJ, Choi HY. Sargassum serratifolium extract attenuates interleukin-1β-induced oxidative stress and inflammatory response in chondrocytes by suppressing the activation of NF-κB, p38 MAPK, and PI3K/Akt. Int J Mol Sci. 2018;19:2308.

    PubMed Central 

    Google Scholar
     

  • 41.

    Uchimura T, Nakamura DS, Hyperlink EM, Noguchi Y, Ōmura S, Sunazuka T, Greenblatt DJ, Zeng L. Erythromycin acts by way of the ghrelin receptor to attenuate inflammatory responses in chondrocytes and keep joint integrity. Biochem Pharmacol. 2019;165:79–90.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 42.

    Bowles RD, Mata BA, Bell RD, Mwangi TK, Huebner JL, Kraus VB, Setton LA. In vivo luminescence imaging of NF-κB exercise and serum cytokine ranges predict ache sensitivities in a rodent mannequin of osteoarthritis. Arthritis Rheumatol. 2014;66:637–46.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 43.

    Yamada EF, Salgueiro AF, Goulart AS, Mendes VP, Anjos BL, Folmer V, Silva MD. Analysis of monosodium iodoacetate dosage to induce knee osteoarthritis: relation with oxidative stress and ache. Int J Rheum Dis. 2019;22:399–410.

    PubMed 
    CAS 

    Google Scholar
     

  • 44.

    Teng P, Liu Y, Dai Y, Zhang HJ, Liu WT, Hu J. Nicotine attenuates osteoarthritis ache and matrix metalloproteinase-9 expression through the α7 nicotinic acetylcholine receptor. J Immunol. 2019;203(2):485–92.

    PubMed 
    CAS 

    Google Scholar
     

  • 45.

    Shetty YC, Patil AE, Jalgaonkar SV, Rege NN, Salgaonkar S, Teltumbde PA, Kshirsagar S, Paresh Koli G, Brahma S. Intra-articular injections of ketamine and 25% dextrose enhance medical and pathological outcomes within the monosodium iodoacetate mannequin of osteoarthritis. J Fundamental Clin Physiol Pharmacol. 2017;28:543–53.

    PubMed 
    CAS 

    Google Scholar
     

  • 46.

    Guingamp C, Pottie PG, Philippe L, Terlain B, Netter P, Gillet P. Mono-iodoacetate-induced experimental osteoarthritis: a dose-response examine of lack of mobility, morphology, and biochemistry. Arthritis Rheum. 1997;40:1670–9.

    PubMed 
    CAS 

    Google Scholar
     

  • 47.

    Pritzker KPH, Homosexual S, Jimenez SA, Ostergaard Okay, Pelletier JP, Revell PA, Salter D, Berg WB. Osteoarthritis cartilage histopathology: grading and staging. Osteoarthr Cartil. 2006;14:13–29.

    CAS 

    Google Scholar
     

  • 48.

    Chung MF, Chia WT, Wan WL, Lin YJ, Sung HW. Managed launch of an anti-inflammatory drug utilizing an ultrasensitive ROS-responsive gas-generating service for localized irritation inhibition. J Am Chem Soc. 2015;137:12462–5.

    PubMed 
    CAS 

    Google Scholar
     

  • 49.

    Kaliamurthi S, Korkmaz AD, Selvaraj G, Polat EG, Wei YK, Almessiere MA, Baykal A, Gu Okay, Wei DQ. Viewing the emphasis on state-of-the-art magnetic nanoparticles: synthesis, bodily properties, and purposes in most cancers theranostics. Curr Pharm Des. 2019;25:1505–23.

    PubMed 
    CAS 

    Google Scholar
     

  • 50.

    Wan SS, Cheng Q, Zeng X, Zhang XZ. A Mn(III)-sealed metal-organic framework nanosystem for redox-unlocked tumor theranostics. ACS Nano. 2019;13:6561–71.

    PubMed 
    CAS 

    Google Scholar
     

  • 51.

    Dai YD, Solar XY, Solar W, Yang JB, Liu R, Luo Y, Zhang T, Tian Y, Lu ZL, He L. H2O2-responsive polymeric micelles with a benzil moiety for environment friendly DOX supply and AIE imaging. Org Biomol Chem. 2019;17:5570–7.

    PubMed 
    CAS 

    Google Scholar
     

  • 52.

    Wilson DS, Dalmasso G, Wang LX, Sitaraman SV, Merlin D, Murthy N. Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA goal irritation and inhibit gene expression within the intestines. Nat Mater. 2010;9:923–8.

    PubMed 
    PubMed Central 
    CAS 

    Google Scholar
     

  • 53.

    Chen DQ, Zhang GQ, Li RM, Guan MR, Wang XY, Zou TJ, Zhang Y, Wang CR, Shu CY, Hong H, Wan LJ. Biodegradable, hydrogen peroxide, and glutathione twin responsive nanoparticles for potential programmable paclitaxel launch. J Am Chem Soc. 2018;140:7373–6.

    PubMed 
    CAS 

    Google Scholar
     

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